Chowdari KV, Bamne M, Wood J, Talkowski ME, Mirnics K, Levitt P,
Lewis DA, Nimgaonkar VL (2008): Linkage disequilibrium patterns and
functional analysis of RGS4 polymorphisms in relation to schizophrenia.
Schizophr Bull 34:118-26.
Garbett K, Ebert P, Mitchell A, Lintas C, Manzi B, Mirnics K, Persico
AM (2008): Immune transcriptome alterations in the temporal cortex of
subjects with autism. Neurobiol Dis: In press.
Garbett K, Gal-Chis R, Gaszner G, Lewis DA, Mirnics K (2008):
Transcriptome alterations in the frontal cortex of subjects with
schizophrenia who committed suicide.
Neuropsychopharmacologica Hungarica, 10 (1): 9-14.
Hashimoto T, Arion D, Unger T, Maldonado-Aviles JG, Morris HM, Volk
DW, Mirnics K, Lewis DA (2008): Alterations in GABA-related
transcriptome in the dorsolateral prefrontal cortex of subjects with
schizophrenia. Mol Psychiatry 13:147-61.
Hashimoto T, Bazmi HH, Mirnics K, Wu Q, Sampson AR, Lewis DA (2008):
Conserved regional patterns of GABA-related transcript expression in the
neocortex of subjects with schizophrenia. Am J Psychiatry
165:479-89.
Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ,
Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P,
Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown
ES, Calabrese JR, Carlezon WA, Jr., Cook EH, Jr., Davidson RJ, Davis M,
Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R,
Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C,
Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF,
Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I,
Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS,
McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A,
Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS,
Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA,
Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ,
Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R,
Yoshikawa T, Young EA, McCandless R (2008): It is time to take a stand
for medical research and against terrorism targeting medical scientists.
Biol Psychiatry 63:725-7.
Lintas C, Sacco R, Garbett K, Mirnics K, Militerni R, Bravaccio C,
Curatolo P, Manzi B, Schneider C, Melmed R, Elia M, Pascucci T, Puglisi-Allegra
S, Reichelt KL, Persico AM (2008): Involvement of the PRKCB1 gene in
autistic disorder: significant genetic association and reduced
neocortical gene expression. Mol Psychiatry. In press.
Arion D, Unger T, Lewis DA, Levitt P, Mirnics K (2007): Molecular
evidence for increased expression of genes related to immune and
chaperone function in the prefrontal cortex in schizophrenia. Biol
Psychiatry 62:711-21.
Arion D, Unger T, Lewis DA, Mirnics K (2007): Molecular markers
distinguishing supragranular and infragranular layers in the human
prefrontal cortex. Eur J Neurosci 25:1843-54.
Campbell DB, D'Oronzio R, Garbett K, Ebert PJ, Mirnics K, Levitt P,
Persico AM (2007): Disruption of cerebral cortex MET signaling in autism
spectrum disorder. Ann Neurol 62:243-50.
Chowdari KV, Northup A, Pless L, Wood J, Joo YH, Mirnics K, Lewis DA,
Levitt PR, Bacanu SA, Nimgaonkar VL (2007): DNA pooling: a
comprehensive, multi-stage association analysis of ACSL6 and SIRT5
polymorphisms in schizophrenia. Genes Brain Behav 6:229-39.
Dutta R, McDonough J, Chang A, Swamy L, Siu A, Kidd GJ, Rudick R,
Mirnics K, Trapp BD (2007): Activation of the ciliary neurotrophic
factor (CNTF) signalling pathway in cortical neurons of multiple
sclerosis patients. Brain 130:2566-76.
Hidvegi T, Mirnics K, Hale P, Ewing M, Beckett C, Perlmutter DH
(2007): Regulator of G Signaling 16 is a marker for the distinct
endoplasmic reticulum stress state associated with aggregated mutant
alpha1-antitrypsin Z in the classical form of alpha1-antitrypsin
deficiency. J Biol Chem 282:27769-80.
Sabatini MJ, Ebert P, Lewis DA, Levitt P, Cameron JL, Mirnics K
(2007): Amygdala gene expression correlates of social behavior in
monkeys experiencing maternal separation. J Neurosci 27:3295-304.
Smith SE, Li J, Garbett K, Mirnics K, Patterson PH (2007): Maternal
immune activation alters fetal brain development through interleukin-6.
J Neurosci 27:10695-702.
Arion D, Sabatini M, Unger T, Pastor J, Alonso-Nanclares L,
Ballesteros-Yanez I, Garcia Sola R, Munoz A, Mirnics K, DeFelipe J
(2006): Correlation of transcriptome profile with electrical activity in
temporal lobe epilepsy. Neurobiol Dis 22:374-87.
Dutta R, McDonough J, Yin X, Peterson J, Chang A, Torres T, Gudz T,
Macklin WB, Lewis DA, Fox RJ, Rudick R, Mirnics K, Trapp BD (2006):
Mitochondrial dysfunction as a cause of axonal degeneration in multiple
sclerosis patients. Ann Neurol 59:478-89.
Ginsberg SD, Mirnics K (2006): Functional genomic methodologies.
Prog Brain Res 158:15-40.
Glorioso C, Sabatini M, Unger T, Hashimoto T, Monteggia LM, Lewis DA,
Mirnics K (2006): Specificity and timing of neocortical transcriptome
changes in response to BDNF gene ablation during embryogenesis or
adulthood. Mol Psychiatry 11:633-48.
Hollingshead D, Korade Z, Lewis DA, Levitt P, Mirnics K (2006): DNA
self-polymers as microarray probes improve assay sensitivity. J
Neurosci Methods 151:216-23.
Koerber HR, Mirnics K, Lawson JJ (2006): Synaptic plasticity in the
adult spinal dorsal horn: the appearance of new functional connections
following peripheral nerve regeneration. Exp Neurol 200:468-79.
Levitt P, Ebert P, Mirnics K, Nimgaonkar VL, Lewis DA (2006): Making
the case for a candidate vulnerability gene in schizophrenia: Convergent
evidence for regulator of G-protein signaling 4 (RGS4). Biol
Psychiatry 60:534-7.
Lewis DA, Mirnics K (2006): Transcriptome alterations in
schizophrenia: disturbing the functional architecture of the
dorsolateral prefrontal cortex. Prog Brain Res 158:141-52.
Mirnics K (2006): Microarrays in brain research: Data quality and
limitations revisited. Current Genomics 7:11-19.
Mirnics K, Levitt P, Lewis DA (2006): Critical appraisal of DNA
microarrays in psychiatric genomics. Biol Psychiatry 60:163-76.
Talkowski ME, Seltman H, Bassett AS, Brzustowicz LM, Chen X, Chowdari
KV, Collier DA, Cordeiro Q, Corvin AP, Deshpande SN, Egan MF, Gill M,
Kendler KS, Kirov G, Heston LL, Levitt P, Lewis DA, Li T, Mirnics K,
Morris DW, Norton N, O'Donovan MC, Owen MJ, Richard C, Semwal P, Sobell
JL, St Clair D, Straub RE, Thelma BK, Vallada H, Weinberger DR, Williams
NM, Wood J, Zhang F, Devlin B, Nimgaonkar VL (2006): Evaluation of a
susceptibility gene for schizophrenia: genotype based meta-analysis of
RGS4 polymorphisms from thirteen independent samples. Biol Psychiatry
60:152-62.
Hollingshead D, Lewis DA, Mirnics K (2005): Platform influence on DNA
microarray data in postmortem brain research. Neurobiol Dis
18:649-55.
Lazarov O, Robinson J, Tang YP, Hairston IS, Korade-Mirnics Z, Lee VM,
Hersh LB, Sapolsky RM, Mirnics K, Sisodia SS (2005): Environmental
enrichment reduces Abeta levels and amyloid deposition in transgenic
mice. Cell 120:701-13.
Lewis DA, Levitt P, Mirnics K (2005): Gene expression changes in
schizophrenia: How do they arise? What do they mean? Clin Neurosci
Res 5:15-21.
Lewis DA, Mirnics K (2005): Genes Dysregulated
in Schizophrenia and Schizophrenia Treatment Methods. USA: University of
Pittsburgh. Patent application 60/736,593.
Middleton FA, Peng L, Lewis DA, Levitt P, Mirnics K (2005): Altered
expression of 14-3-3 genes in the prefrontal cortex of subjects with
schizophrenia. Neuropsychopharmacology 30:974-83.
Mirnics K, Korade Z, Arion D, Lazarov O, Unger T, Macioce M, Sabatini
M, Terrano D, Douglass KC, Schor NF, Sisodia SS (2005):
Presenilin-1-dependent transcriptome changes. J Neurosci
25:1571-8.
Mirnics ZK, Yan C, Portugal C, Kim TW, Saragovi HU, Sisodia SS,
Mirnics K, Schor NF (2005): P75 neurotrophin receptor regulates
expression of neural cell adhesion molecule 1. Neurobiol Dis
20:969-85.
Unger T, Korade Z, Lazarov O, Terrano D, Schor NF, Sisodia SS,
Mirnics K (2005): Transcriptome differences between the frontal cortex
and hippocampus of wild-type and humanized presenilin-1 transgenic mice.
Am J Geriatr Psychiatry 13:1041-51.
Unger T, Korade Z, Lazarov O, Terrano D, Sisodia SS, Mirnics K
(2005): True and false discovery in DNA microarray experiments:
transcriptome changes in the hippocampus of presenilin 1 mutant mice.
Methods 37:261-73.
Lewis DA, Mirnics K, Levitt P (2004): Transcriptomes in
Schizophrenia: Assessing Altered Gene Expression with Microarrays. In
Keshavan MS, Kennedy JL, Murray RM (eds), Neurodevelopment and
Schizophrenia. Cambridge, UK: Cambridge University Press, pp
210-223.
Mirnics K, Levitt P, Lewis DA (2004): DNA microarray analysis of
postmortem brain tissue. Int Rev Neurobiol 60:153-81.
Mirnics K, Pevsner J (2004): Progress in the use of microarray
technology to study the neurobiology of disease. Nat Neurosci
7:434-9.
Mirnics ZK, Caudell E, Gao Y, Kuwahara K, Sakaguchi N, Kurosaki T,
Burnside J, Mirnics K, Corey SJ (2004): Microarray analysis of
Lyn-deficient B cells reveals germinal center-associated nuclear protein
and other genes associated with the lymphoid germinal center. J
Immunol 172:4133-41.
Pongrac JL, Middleton FA, Peng L, Lewis DA, Levitt P, Mirnics K
(2004): Heat shock protein 12A shows reduced expression in the
prefrontal cortex of subjects with schizophrenia. Biol Psychiatry
56:943-50.
Hashimoto T, Volk DW, Eggan SM, Mirnics K, Pierri JN, Sun Z, Sampson
AR, Lewis DA (2003): Gene expression deficits in a subclass of GABA
neurons in the prefrontal cortex of subjects with schizophrenia. J
Neurosci 23:6315-26.
Levitt P, Chowdari KV, Nimgaonkar VL, Mirnics K
(2003): Methods and systems for facilitating the diagnosis and treatment
of schizophrenia. USA: Vanderbilt University. Patent application
20030113721.
Mirnics K (2003): Schizophrenia as a disease of synapse: Gene
microarray studies. In Levitt P, Lewis DA, DeFelipe J (eds), Vol 149.
Madrid, Spain: Instituto Juan March de Estudios e Investigaciones, pp
36-37.
Mirnics K (2003): Analysis of Mental Disorders Using DNA Microarrays.
In Mallet J (ed), Neuroscience at the Post-genomic Era. Paris:
IPSEN Foundation, pp 25-42.
Mirnics ZK, Mirnics K, Terrano D, Lewis DA, Sisodia SS, Schor NF
(2003): DNA microarray profiling of developing PS1-deficient mouse brain
reveals complex and coregulated expression changes. Mol Psychiatry
8:863-78.
Chowdari KV, Mirnics K, Semwal P, Wood J, Lawrence E, Bhatia T,
Deshpande SN, B KT, Ferrell RE, Middleton FA, Devlin B, Levitt P, Lewis
DA, Nimgaonkar VL (2002): Association and linkage analyses of RGS4
polymorphisms in schizophrenia. Hum Mol Genet 11:1373-80.
Middleton FA, Mirnics K, Pierri JN, Lewis DA, Levitt P (2002): Gene
expression profiling reveals alterations of specific metabolic pathways
in schizophrenia. J Neurosci 22:2718-29.
Mirnics K (2002): Microarrays in brain research: Data quality and
limitations. Current Genomics 3:13-19.
Pongrac J, Middleton FA, Lewis DA, Levitt P, Mirnics K (2002): Gene
expression profiling with DNA microarrays: advancing our understanding
of psychiatric disorders. Neurochem Res 27:1049-63.
Mirnics K (2001): Gene Expression Microarrays in Brain Research: It
is all about design! In Geschwind DH (ed), DNA Microarray Workshop
Syllabus. Rockville, MD: Society for Neuroscience, pp 56-67.
Mirnics K (2001): Microarrays in brain research: the good, the bad
and the ugly. Nat Rev Neurosci 2:444-7.
Mirnics K, Lewis DA (2001): Genes and subtypes of schizophrenia.
Trends Mol Med 7:281-3.
Mirnics K, Lewis DA, Levitt P (2001): DNA Mircroarray Studies of
Human Brain Disorders. In Moldin S, Chin H (eds), Methods in
Neurogenetics. Boca Raton: CRC Press, LLC, pp 188-217.
Mirnics K, Middleton FA, Lewis DA, Levitt P (2001): Analysis of
complex brain disorders with gene expression microarrays: schizophrenia
as a disease of the synapse. Trends Neurosci 24:479-86.
Mirnics K, Middleton FA, Lewis DA, Levitt P (2001): The human genome:
gene expression profiling and schizophrenia. Am J Psychiatry
158:1384.
Mirnics K, Middleton FA, Lewis DA, Levitt P (2001): Delineating novel
signature patterns of altered gene expression in schizophrenia using
gene microarrays. ScientificWorldJournal 1:114-6.
Mirnics K, Middleton FA, Stanwood GD, Lewis DA, Levitt P (2001):
Disease-specific changes in regulator of G-protein signaling 4 (RGS4)
expression in schizophrenia. Mol Psychiatry 6:293-301.
Mirnics K, Middleton FA, Marquez A, Lewis DA, Levitt P (2000):
Molecular characterization of schizophrenia viewed by microarray
analysis of gene expression in prefrontal cortex. Neuron
28:53-67.